Cancer of the supernumerary ovary in Mayer-Rokitansty-Küster-Hauser Syndrome: A case report
نویسندگان
چکیده
Mayer-Rokitansty-Küster-Hauser (MRKH) syndrome is a Müllerian anomaly that presents with varying degrees of uterovaginal aplasia and is secondarily associated with cervicothoracic, auditory and skeletal anomalies. However, MRKH syndrome patients have normal and functional ovaries. A supernumerary ovary is an extremely rare form of an ectopic ovary and there are no reported cases of MRKH syndrome with cancer of the supernumerary ovary in the current literature. A 31-year-old female with a history of MRKH syndrome that was diagnosed 4 years previously presented with abdominal pain and a suspected malignant pelvic mass was identified. During the staging surgery, both ovaries were separated from the main mass, observed and removed. A third ovary was discovered in the pelvic mass and the diagnosis of primary ovarian cancer from the third ovary was confirmed by immunohistochemistry. We report the first known case of cancer of the supernumerary ovary in a patient with MRKH syndrome. Although both ovaries were confirmed to be normal in the patient with MRKH syndrome, we propose that an ovarian neoplasm should be considered in the diagnosis of a pelvic mass.
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Successful Surgical Treatment for Vaginal Agenesis: Report of Two Cases of Mayer–Rokitansky–Küster–Hauser (MRKH) Syndrome
Introduction: Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is a rare disorder in women which identified as agenesis of vagina and hypoplasia or agenesis of uterine. Case presentation: in this study, two female cases (17, and 19 years old) diagnosed with MRKH (first one type 2, and second one type 1) are described. Both patients were presented with amenorrhea, and absence of vagina orifice. On...
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1. Morcel K, Camborieux L. Programmede recherches sur les aplasiesmüllériennes (PRAM)andGuerrierD.Mayer–Rokitansky–Küster–Hauser syndrome.Orphanet J Rare Dis. 2007;2:13. 2. Strübbe EH, Cremers CW, Wilemsen WN, Rolland R, Thijn CJ. The Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome without and with associated features: two separate entities? Clin Dysmorphol. 1994;3:192–9. 3. Vasquez JC, De la Ro...
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